De novo, Foxp3+iT reg cells were found in the periphery (and, importantly, not the thymus;Fig Jun 17, 2025 acusticavisual
This hypoxic microenvironment has been demonstrated to be highly immunosuppressive for the CD4+and CD8+effector function, leading to exhaustion and anergic phenotypes (14,218) Jun 14, 2025 acusticavisual
Nevertheless, different studies have shown that some Wuhan-Hu-1-based COVID-19 vaccines can protect against SARS-CoV-2 VoC morbidity and mortality in different animal models, although with different degrees of infection protection (2332) Jun 13, 2025 acusticavisual